FTY720 MEDIATES APOPTOSIS-INDEPENDENT LYMPHOPENIA IN HUMAN RENAL ALLOGRAFT RECIPIENTS DIFFERENT EFFECTS ON CD62LAND CCR5T LYMPHOCYTES

Autor: Böhler, Torsten, Waiser, Johannes, Schütz, Manuela, Dragun, Duska, Neumayer, Hans-H., Budde, Klemens
Zdroj: Transplantation; May 2004, Vol. 77 Issue: 9 p1424-1432, 9p
Abstrakt: The sphingolipid FTY720 (FTY), a novel immune modulator, induces lymphopenia and prevents allograft rejection. This study was designed to study the effect of FTY on lymphocyte subpopulations and apoptosis in stable renal allograft recipients.
Databáze: Supplemental Index