Thrombotic Microangiopathy after Allogeneic Blood and Marrow Transplantation Is Associated with Dose-Intensive Myeloablative Conditioning Regimens, Unrelated Donor, and Methylprednisolone T-Cell Depletion

Autor: Hahn, Theresa, Alam, Arif Raza, Lawrence, David, Ford, LaurieAnn, Baer, Maria R., Bambach, Barbara, Bernstein, Zale P., Czuczman, Myron S., Silva, Joaquin, Slack, James L., Wetzler, Meir, Becker, Joanne, McCarthy, Philip L.
Zdroj: Transplantation; November 2004, Vol. 78 Issue: 10 p1515-1522, 8p
Abstrakt: Allogeneic blood and marrow transplantation (BMT)-associated thrombotic microangiopathy (TM) contributes to transplant-related morbidity and mortality. This report examines the incidence of and risk factors for allogeneic BMT-associated TM in two patient cohorts treated before and after changes in myeloablative conditioning regimen intensity (high vs. standard intensity).
Databáze: Supplemental Index