| Autor: |
Shimmura, Hiroaki, Tanabe, Kazunari, Ishida, Hideki, Tokumoto, Tadahiko, Ishikawa, Nobuo, Miyamoto, Naoshi, Shirakawa, Hiroki, Setoguchi, Kiyoshi, Nakajima, Ichiro, Fuchinoue, Shouhei, Teraoka, Satoshi, Toma, Hiroshi |
| Zdroj: |
Transplantation; October 2005, Vol. 80 Issue: 7 p985-988, 4p |
| Abstrakt: |
In this study, we examined the impact of preoperative anti-A/B antibody titers on the results of ABO-incompatible living kidney transplantation (LKT). In all, 167 recipients underwent ABO-incompatible LKT at our institution between 1989 and 2002. These patients were subdivided into those transplanted under cyclosporine with azathioprine or mizoribine (Group 1, n78) and those transplanted under tacrolimus or mycophenolate mofetil (Group 2, n89). Overall patient survival at 5 and 10 years was 93.8% and 88.0%, respectively. Overall graft survival at 5 and 10 years was 76.9% and 55.9%, respectively. Graft survival in the patients with anti-A/B IgG titers over 1:128 was significantly lower in group 1, whereas no significant correlation between the anti-A/B IgG titers and graft survival was found in group 2. In conclusion, no correlation between anti-A/B antibody titers and the results of ABO-incompatible LKT was seen after tacrolimus or mycophenolate mofetil application. |
| Databáze: |
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