TISSUE TRANSGLUTAMINASE A MEDIATOR AND PREDICTOR OF CHRONIC ALLOGRAFT NEPHROPATHY

Autor: Johnson, Timothy S., Abo-Zenah, Hamdy, Skill, James N., Bex, Samantha, Wild, Graham, Brown, Colin B., Griffin, Martin, Nahas, A. Meguid El
Zdroj: Transplantation; June 2004, Vol. 77 Issue: 11 p1667-1675, 9p
Abstrakt: The precise mechanisms underlying the development of chronic allograft nephropathy (CAN) and the associated renal fibrosis remain uncertain. The protein-crosslinking enzyme, tissue transglutaminase (tTg), has recently been implicated in renal fibrosis.
Databáze: Supplemental Index