| Autor: |
Dehamer, Dale L., Goodman, Joan W. |
| Zdroj: |
Transplantation; May 1971, Vol. 11 Issue: 5 p474-477, 4p |
| Abstrakt: |
Hemopoietic tissues are poorly repopulated in lethally irradiated mice by bone marrow transplanted from certain homologous or heterologous animals. Administration of marrow donortype thymocytes has been shown to augment repopulation. We have confirmed augmentation of repopulation, using mitotic indices of spleens 8 days after injection of bone marrow cells or thymocytes or both, and we have shown that most of the repopulating cells are derived from the donor marrow. Using female rats as bone marrow donors and male rats as thymus donors, and vice versa, we found that 93.1 of the dividing cells in repopulated mouse spleen were of rat bone marrow origin. About 1.0 of the dividing cells were of mouse origin, and 5.9 were derived from rat thymus. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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