| Autor: |
Rossi, Cristina, Zambruni, Andrea, Ansaloni, Fabio, Casadei, Andrea, Morelli, Cristina, Bernardi, Mauro, Trevisani, Franco |
| Zdroj: |
Transplantation; September 2004, Vol. 78 Issue: 6 p938-940, 3p |
| Abstrakt: |
Portal vein thrombosis (PVT) is an uncommon cause for presinusoidal portal hypertension and can occur even in liver-graft recipients. Interventional radiology by percutaneous approach may represent a valid and less invasive alternative to surgical treatment. We describe three cases of PVT (2 liver-transplant patients and a cirrhotic patient candidate for liver transplantation) treated by combined mechanical and pharmacologic thrombolysis. The Arrow-Trerotola device was used along with the infusion of urokinase by way of a percutaneous-transhepatic approach. In all cases, a recanalization of the portal system was obtained and maintained during the follow-up. The best result was achieved when mechanical thrombectomy was performed before urokinase infusion. The combined locoregional treatment with mechanical thrombectomy and pharmacologic thrombolysis appears to be a promising approach for PVT because of its rapid and durable effect and its ability to reduce the dose of urokinase required to achieve recanalization. |
| Databáze: |
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