ACTIVATION OF MITOCHONDRIAL APOPTOTIC PATHWAYS IN HUMAN RENAL ALLOGRAFTS AFTER ISCHEMIAREPERFUSION INJURY

Autor: Castaneda, M. Patricia, SwiateckaUrban, Agnieszka, Mitsnefes, Mark M., Feuerstein, Dianne, Kaskel, Frederick J., Tellis, Vivian, Devarajan, Prasad
Zdroj: Transplantation; July 2003, Vol. 76 Issue: 1 p50-54, 5p
Abstrakt: Ischemiareperfusion injury in cadaveric CAD kidney allografts is associated with tubular cell injury, delayed graft function, and an increased incidence of acute and chronic rejection. We tested the hypothesis that activation of specific apoptotic pathways represents a mechanism for tubular cell death after CAD kidney transplantation.
Databáze: Supplemental Index