| Autor: |
Brambilla, G, Parodi, S, CAVANNA, M, Baldini, L |
| Zdroj: |
Transplantation; January 2024, Vol. 10 Issue: 1 p100-105, 6p |
| Abstrakt: |
Short intensive treatment with N-diazoacetylglycine amide (DGA) significantly prolonged the median survival time of skin grafts in H-2-incompatible mice and was effective in allowing the growth of L1210 leukemia allografts in the C57BL/6 strain and the development of Ehrlich ascites carcinoma in immunized mice. Depending on the experimental model employed, maximal immunodepressive effects resulted from the administration of DGA before or shortly after the antigen, and its effectiveness was comparable with, or even higher than that of, azathioprine to be rather long lasting, and its mode of action seemed to be different from that of azathioprine. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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