Autor: |
Seckel, Brooke Rutledge, Ryan, Sheila E., Gagne, Roland G., Chiu, Tin Ho, Watkins, Elton |
Zdroj: |
Plastic and Reconstructive Surgery; December 1986, Vol. 78 Issue: 6 p793-798, 6p |
Abstrakt: |
Nerve regeneration across a gap in peripheral nerve has been achieved through various nonneural nerve guides in both lower and primate species. This technique can only be useful if the regenerated nerve cable grows specifically to and reinnervates the appropriate distal target. In this study, the proximal peroneal fascicle of rat sciatic nerve was inserted into the proximal limb of a Yshaped nerve guide. Distal peroneal and tibial fascicles were placed within the two distal limbs of the same Y. The proximal peroneal nerve grew preferentially by a 21 ratio to the appropriate distal peroneal fascicle suggesting that targetspecific reinnervation is possible through a nerve guide. |
Databáze: |
Supplemental Index |
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