Urokinase Protocol for FreeFlap Salvage following Prolonged Venous Thrombosis

Autor: Serletti, Joseph M., Moran, Steven L., Orlando, Greg S., O'Connor, Timothy, Herrera, Raul H.
Zdroj: Plastic and Reconstructive Surgery; November 1998, Vol. 102 Issue: 6 p1947-1953, 7p
Abstrakt: The incidence of freeflap failure is reported at 4 to 5 percent. Often, these failures are attributed to postoperative venous thrombosis with salvage rates reported at 42 percent. The use of thrombolytics has been effective in laboratory protocols however, there have been only case reports to substantiate their use in humans. In this study, we establish a protocol for the administration of urokinase for postoperative venous thrombosis.
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