| Autor: |
Bruce, R. S., Carr, T. E. F., Collins, Mary E. |
| Zdroj: |
Health Physics; August 1962, Vol. 8 Issue: 4 p397-406, 10p |
| Abstrakt: |
A study has been made of factors which affect the absorption of the nitrosyl complex of Ru106from the gastrointestinal tract of the rat. Absorption is normally complete within 2 hr. The rate of transit of the ruthenium through the gut and chemical combination with the contents may account for this limited period of absorption. However, about 20 per cent of a dose is absorbed into the wall of the small intestine during the first hour while the total uptake into the rest of the body is only 2–4 per cent. It appears, therefore, that passage from the gut wall into the blood is the limiting stage in the absorption of nitrosyl-ruthenium. Fasting rats before the administration of ruthenium influences this stage and the 24-hr absorption into the body is increased threefold. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
