A Randomized Trial Comparing the Levonorgestrel Intrauterine System and Thermal Balloon Ablation for Heavy Menstrual Bleeding

Autor: Busfield, R A., Farquhar, C M., Sowter, M C., Lethaby, A, Sprecher, M, Yu, Y, Sadler, L C., Brown, P, Johnson, N
Zdroj: Obstetrical and Gynecological Survey; July 2006, Vol. 61 Issue: 7 p444-445, 2p
Abstrakt: Because hysteroscopic endometrial resection and ablation for menorrhagia require a high level of skill to perform effectively and safely, a variety of global ablation devices have been designed for use by those having limited experience with hysteroscopy. They include ablation using a thermal balloon, microwaves, or diffused laser energy; cryoablation; and instillation of hot saline. The present investigators carried out a prospective, randomized trial comparing thermal balloon ablation with the levonorgestrel intrauterine system (LNG-IUS), an intrauterine device that releases 20 g levonorgestrel every 24 hours over 5 years. Forty women 25 to 50 years of age with self-described heavy menstrual bleeding were assigned to the LNG-IUS and 39 others to thermal balloon ablation. Menstrual blood loss was estimated using a pictorial bleeding assessment chart after 3, 6, 9, 12, and 24 months.
Databáze: Supplemental Index