| Autor: |
DeSimone, Christopher P., Crisp, Meredith P., Ueland, Frederick R., DePriest, Paul D., Nagell, John R. van, Lele, Subodh M., Modesitt, Susan C. |
| Zdroj: |
Obstetrical and Gynecological Survey; December 2006, Vol. 61 Issue: 12 p777-778, 2p |
| Abstrakt: |
Although vulvar cancer still accounts for approximately 5% of gynecologic malignancies, the incidence of vulvar intraepithelial neoplasia (VIN) has nearly doubled in the past 2 decades. When VIN 3 is severe and not treated, this lesion may progress to frank cancer. Excision is most often preferred to obtain negative surgical margins and to rule out occult invasive cancer—present in up to 20% of patients with biopsy-proved VIN 3. Traditionally, a margin of 2 to 3 cm has been recommended after vulvectomy. This prospective study compared gross surgical margins with final fixed gross margins in 27 women over age 18 who had biopsy-proved VIN 3 or vulvar carcinoma. More than 80% of the women smoked, and nearly 60% had a history of genital dysplasia. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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