Autor: |
Grigoriadis, Sophie, VonderPorten, Emily H., Mamisashvili, Lana, Tomlinson, George, Dennis, Cindy-Lee, Koren, Gideon, Steiner, Meir, Mousmanis, Patricia, Cheung, Amy, Ross, Lori E. |
Zdroj: |
Obstetrical and Gynecological Survey; May 2014, Vol. 69 Issue: 5 p239-241, 3p |
Abstrakt: |
Decisions about using antidepressants to treat major depressive disorder during pregnancy are complex. A potential adverse effect is persistent pulmonary hypertension of the newborn (PPHN), with an estimated baseline prevalence of 1.9 of 1000 live births. Symptoms can range from mild respiratory distress to hypoxia. Although a potential association between maternal use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy and PPHN was noted in 2006, subsequent published evidence is contradictory. This systematic review and meta-analysis was undertaken to determine whether a relationship exists between prenatal exposure to antidepressants and PPHN, with consideration of known risk factors. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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