| Abstrakt: |
Twenty-two women and 18 men undergoing intra-arterial digital subtraction angiography were enrolled in an open-label, noncomparative study to assess the efficacy, safety, and patient tolerance of the contrast medium ioversol. The quality of radiographs generated was excellent in 60.0 of the studies, diagnostic in 37.5, and nondiagnostic in 2.5. There were no clinically significant drug-related changes in vital signs or laboratory tests among the patients, and no drug-related adverse effects were reported. Heat and pain related to injection of ioversol were graded on a four-point scale, with 0 indicating none and 3 indicating severe. The average scores were 1.3 for heat and 0.1 for pain. In this study, ioversol was a safe and effective contrast medium for angiography and was associated with a low incidence of patient discomfort. |
