| Autor: |
VázquezMellado, Janitzia, Vázquez, Silvia Guzmán, Barrientos, Jorge Cazarín, Ríos, Verónica Gómez, BurgosVargas, Rubén |
| Zdroj: |
Journal of Clinical Rheumatology; October 2000, Vol. 6 Issue: 5 p266-268, 3p |
| Abstrakt: |
This is a case report of a 36yearold male with tophaceous gout for 16 years. He started therapy with 300 mgday of allopurinol. He had received variable dexamethasone doses by selfprescription for 16 years. When allopurinol was initiated, he had hyperuricemia and normal renal function. Twenty days after starting allopurinol, he presented diffuse maculopapular rash, conjunctivitis, increase in serum creatinine values, leukocytosis and eosinophilia and the diagnosis of allopurinol hypersensitivity AH syndrome was made. He completely recovered from the AH and renal function normalized. However, the gout worsened over the following years in spite of treatment with benzobromarone, low doses of prednisone, and colchicine. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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