| Autor: |
Wilke, Leslie, Prince-Fiocco, Marilynn, Fiocco, Guy Peter |
| Zdroj: |
Journal of Clinical Rheumatology; June 2014, Vol. 20 Issue: 4 p179-182, 4p |
| Abstrakt: |
Microscopic polyangiitis (MPA) is a rare systemic vasculitis, antineutrophil cytoplasmic antibody associated, characterized by necrotizing small vessel involvement with few or no immune complex deposits. Necrotizing glomerulonephritis is common. Pulmonary capillaritis causing alveolar hemorrhage and hemoptysis is well recognized, but most case series are reported in the nephrology literature and emphasize renal considerations. We present a single-center 10-year retrospective review of 40 patients meeting the 2012 Revised Chapel Hill Nomenclature of MPA, with specific p-antineutrophil cytoplasmic antibody and myeloperoxidase positivity, emphasizing initial and subsequent pulmonary manifestations. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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