The use of topiramate in refractory status epilepticus

Autor: Towne, A.R., Garnett, L.K., Waterhouse, E.J., Morton, L.D., DeLorenzo, R.J.
Zdroj: Neurology (Ovid); January 2003, Vol. 60 Issue: 2 p332-334, 3p
Abstrakt: In cases of refractory status epilepticus (RSE) unresponsive to sequential trials of multiple agents, a suspension of topiramate administered via nasogastric tube was effective in aborting RSE, including one patient in a prolonged pentobarbital coma. Effective dosages ranged from 300 to 1,600 mg/d. Except for lethargy, no adverse events were reported.
Databáze: Supplemental Index