Long-term clinical outcome of primary progressive MS Predictive value of clinical and MRI data

Autor: Sastre-Garriga, J, Ingle, G T., Rovaris, M, Téllez, N, Jasperse, B, Altmann, D R., Benedetti, B, Stevenson, V L., Cercignani, M, Leary, S M., Barkhof, F, Brochet, B, Dousset, V, Filippi, M, Montalban, X, Kalkers, N F., Polman, C H., Rovira, À, Miller, D H., Thompson, A J.
Zdroj: Neurology (Ovid); August 2005, Vol. 65 Issue: 4 p633-635, 3p
Abstrakt: The authors sought to identify clinical and MRI predictors of outcome in primary progressive multiple sclerosis (PPMS). Clinical and MRI assessments were performed at baseline and 2 and 5 years (clinical only). At baseline, disease duration, expanded disability status scale (EDSS) and brain volume predicted outcome. Adding short-term change variables, baseline EDSS, changes in T2 lesion load and cord area, and number of new lesions were predictive. Clinical and MRI variables predict long-term outcome in PPMS.
Databáze: Supplemental Index