Lethal African trypanosomiasis in a traveler MRI and neuropathology

Autor: Braakman, Hilde M.H., Molengraft, Fred J.J.M. van de, Hubert, Wim W.A., Boerman, Dolf H.
Zdroj: Neurology (Ovid); April 2006, Vol. 66 Issue: 7 p1094-1096, 3p
Abstrakt: The authors report a case of human African trypanosomiasis with CNS involvement caused by Trypanosoma brucei rhodesiensein a 52-year-old woman, which relapsed after melarsoprol treatment. After a second regimen, she developed a severe toxic polyneuropathy, progressing to coma and eventually death. MRI revealed rapidly progressive multiple white matter lesions as well as damage of the central gray matter and cortex. The autopsy results confirmed the diagnosis of human African trypanosomiasis.
Databáze: Supplemental Index