-Synuclein and Parkinson disease susceptibility

Autor: Winkler, S, Hagenah, J, Lincoln, S, Heckman, M, Haugarvoll, K, Lohmann-Hedrich, K, Kostic, V, Farrer, M, Klein, C
Zdroj: Neurology (Ovid); October 2007, Vol. 69 Issue: 18 p1745-1750, 6p
Abstrakt: Mutations in the -synuclein(SNCA) gene have been shown to be responsible for a rare familial form of Parkinson disease (PD). Furthermore, polymorphic variants in multiple regions of the gene have been associated with susceptibility to idiopathic PD in different populations.
Databáze: Supplemental Index