| Autor: |
Reger, M A., Watson, G S., Green, P S., Wilkinson, C W., Baker, L D., Cholerton, B, Fishel, M A., Plymate, S R., Breitner, J C.S., DeGroodt, W, Mehta, P, Craft, S |
| Zdroj: |
Neurology (Ovid); February 2008, Vol. 70 Issue: 6 p440-448, 9p |
| Abstrakt: |
Reduced brain insulin signaling and low CSF-to-plasma insulin ratios have been observed in patients with Alzheimer disease (AD). Furthermore, intracerebroventricular or IV insulin administration improve memory, alter evoked potentials, and modulate neurotransmitters, possibly by augmenting low brain levels. After intranasal administration, insulin-like peptides follow extracellular pathways to the brain within 15 minutes. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
