| Autor: |
Prodan, C.I., Ross, E.D., Stoner, J.A., Cowan, L.D., Vincent, A.S., Dale, G.L. |
| Zdroj: |
Neurology (Ovid); January 2011, Vol. 76 Issue: 3 p247-252, 6p |
| Abstrakt: |
Coated-platelets are a subset of platelets produced by dual-agonist activation with collagen and thrombin. These platelets retain full-length amyloid precursor protein on their surface, are elevated in patients with amnestic as compared to nonamnestic mild cognitive impairment (MCI), and correlate with disease progression in Alzheimer disease (AD). Prompted by these findings, we investigated the association between coated-platelet production in amnestic MCI and rate of progression to AD. |
| Databáze: |
Supplemental Index |
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