MRI correlates of cognitive decline in CADASIL

Autor: Liem, M K., Oberstein, S A.J. Lesnik, Haan, J, Neut, I L. van der, Ferrari, M D., Buchem, M A. van, Middelkoop, H A.M., van der Grond, J
Zdroj: Neurology (Ovid); January 2009, Vol. 72 Issue: 2 p143-148, 6p
Abstrakt: Cognitive decline is one of the clinical hallmarks of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a cerebrovascular disease caused by NOTCH3mutations. In this 7-year follow-up study, we aimed to determine whether there are associations between the different radiologic hallmarks in CADASIL and decline in specific cognitive domains.
Databáze: Supplemental Index