| Autor: |
ALFA, M. J., EMBREE, J. E., DEGAGNE, P., OLSON, N., LERTZMAN, J., MACDONALD, K. S., MACDONALD, N. T., HALL, P. F. |
| Zdroj: |
The Pediatric Infectious Disease Journal; May 1995, Vol. 14 Issue: 5 p341-345, 5p |
| Abstrakt: |
This study assessed maternal genital colonization and subsequent neontal transmission rate of Ureaplsma urealyticumin pregnant women in an average socioeconomic population. In addition very low birth weight infants were assessed to determine whether the presence of U. urealyticumcorrelated with increased risk of developing respiratory problems. The study group consisted of 108 sequential full term mothers and 104 preterm mothers delivering in a tertiary care hospital in central Canada. The genital carriage rates (assessed using placental sampling) of ureaplsamas in term and preterm mothers were 25.9 and 19.2, respectively (P= 0.3185). Acquisition of ureaplasmas in the neonatal respiratory tract of neonates occurred significantly (P= 0.0182) more often in preterm neonates (11 of 130;8.5) than in term neonates (2 of 110;0.9). Very low brith weight (VLBW) infants (<1500 g) were at greater risk (P= 0.042) of acquiring ureaplasmas in their respiratory tracts (5 of 26; 19) than larger preterm neonates (6 of 104; 5.8). All VLBW infants with respiratory colonization by ureaplasmas (5 of 5) developed bronchopulmonary dysplasia compared with 33 (7 of 21) of VLBW neonates without ureaplasmas (P= 0.028). This difference in bronchopulmonary dysplasia develoment among VLBW infants was independent of further stratification by birth weight. These VLBW neonates with ureaplasmas also stayed significantly (P= 0.037) longer in the neonatal intensive care unit (43.6 ± 10.4 days) than did other preterm neonates (22.1 ± 20.8 days). Our results demonstrate thet VLBW preterm neonates have increased risk of acquiring U. urealyticum.The presence of this organism in their respiratory tracts corresponds with increased likelihood of their developing bronchopulmonary dysplasia and requiring significantly prolonged neonatal intensive care unit admission. |
| Databáze: |
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