| Autor: |
Monpoux, Fabrice, Kurzenne, Jean-Yves, Sirvent, Nicolas, Cottalorda, Jacqueline, Boutté, Patrick |
| Zdroj: |
Journal of Pediatric Hematology / Oncology; September 1999, Vol. 21 Issue: 5 p441-443, 3p |
| Abstrakt: |
Immune thrombocytopenia (IT) is a frequently occurring disease in childhood and a well known complication of HIV infection. Splenectomy is a part of the treatment strategy for severe chronic IT. However, overwhelming infections after splenectomy have limited its use, especially in young children. A 7-year-old child with maternal-fetal HIV-1 infection and related thrombocytopenia underwent splenectomy after previous treatment failed to improve her platelet count. Approximately 75 of the spleen was removed. The postoperative period was uncomplicated, and the platelet count increased significantly to greater than 500,000/mm3. Ultrasonographic examination performed 3 months later showed a stable volume of the spleen stump (40 × 40 × 20 mm) with effective “vascu-larization.” The platelet count 12 months after surgery showed a sustained increase greater than 150,000 cell/mm3. Subtotal splenectomy may be a safe and effective alternative for patients with HIV and immune thrombocytopenia. |
| Databáze: |
Supplemental Index |
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