| Autor: |
PELTIER, P., FAUCAL, P. DE, CHETANNEAU, A., CHATAL, J. -F. |
| Zdroj: |
Nuclear Medicine Communications; September 1990, Vol. 11 Issue: 9 p631-638, 8p |
| Abstrakt: |
A new method of producing aerosols (technegas) in which 99Tcmis bound to carbon atoms (99Tcm-C) was evaluated by comparing 99Tcm-C images with those obtained with 81Krmin the same patients. Twenty-five patients with suspected pulmonary embolism (PE) were studied. Immediately after the last 99Tcm-C view, the patients remained in supine position and inhaled 81Krmat tidal volume. Immediately after the 81Krmventilation views were recorded, 4–7 mCi of MAA were injected IV. The same four views (ant, lop, rop, post) were recorded after inhalation of 99Tcm-C and 81Krm(200 kcounts) and 99TcmMAA injection (400 kcounts). The mean penetration index of 99Tcm-C (0.91) was lower than that of 81Krm(1.04) (P<0.03). The apex to base lung distribution of 99Tcm-C and 81Krmappeared to be similar. The mean heterogeneity of 99Tcmdistribution was 23, greater than that of 81Krm(14) (P= 10-4). The 99Tcm-C ventilation image quality was considered very good for 16 patients and good for 6 others. Significant foci of high bronchial uptake were infrequent. Interpretation of the examinations performed after inhalation of 99Tcm-C and 81Krmwas concordant in all cases. No patient had an 81Krm/99TcmMAA examination suggestive of PE when 99Tcm-C/99TcmMAA indicated a low probability of PE, and vice versa. 99Tcm-C aerosols enable good quality ventilation images to be obtained in nearly all cases. Thus 99Tcm-C aerosols could be used in preference to 81Krmin ventilation studies for the diagnosis of PE. |
| Databáze: |
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