Terminally Modified Oligodeoxynucleotides Directed Against p53 in an Orthotopic Xenograft Model A Novel Adjuvant Treatment Strategy for Pancreatic Ductal Carcinoma
Autor: | Tepel, Jürgen, Kruse, Marie-Luise, March, Christina, Fiedler, Alexander, Kapischke, Matthias, Ketterer, Thomas, Sipos, Bence, Kremer, Bernd, Kalthoff, Holger |
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Zdroj: | Pancreas; January 2004, Vol. 28 Issue: 1 p1-12, 12p |
Abstrakt: | Investigation of a terminally modified oligodeoxynucleotide (ODN) directed against p53 mRNA (p53-3′ polyethylene glycol–5′ tocopherol ODN as a novel drug for pancreatic ductal carcinoma therapy in vitro and in vivo. |
Databáze: | Supplemental Index |
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