Terminally Modified Oligodeoxynucleotides Directed Against p53 in an Orthotopic Xenograft Model A Novel Adjuvant Treatment Strategy for Pancreatic Ductal Carcinoma

Autor: Tepel, Jürgen, Kruse, Marie-Luise, March, Christina, Fiedler, Alexander, Kapischke, Matthias, Ketterer, Thomas, Sipos, Bence, Kremer, Bernd, Kalthoff, Holger
Zdroj: Pancreas; January 2004, Vol. 28 Issue: 1 p1-12, 12p
Abstrakt: Investigation of a terminally modified oligodeoxynucleotide (ODN) directed against p53 mRNA (p53-3′ polyethylene glycol–5′ tocopherol ODN as a novel drug for pancreatic ductal carcinoma therapy in vitro and in vivo.
Databáze: Supplemental Index