Modulatory effect of insulin on release of calcium from human fibroblasts by angiotensin II

Autor: Ceolotto, Giulio, Pessina, Achille C., Iori, Elisabetta, Monari, Alessandra, Trevisan, Roberto, Winkleswski, Pawel, Semplicini, Andrea
Zdroj: Journal of Hypertension; April 1998, Vol. 16 Issue: 4 p487-493, 7p
Abstrakt: Angiotensin II stimulates synthesis and deposition of collagen and might contribute to the vascular and cardiac dysfunction associated with arterial hypertension. Insulin attenuates angiotensin II-induced responses of intracellular Ca2concentration ([Ca2]) in many cell types but this effect is less in insulin-resistant states. The mechanisms of the interaction between insulin and angiotensin II are still not known.
Databáze: Supplemental Index