Light-induced vs. bradykinin-induced relaxation of coronary arteries do S-nitrosothiols act as endothelium-derived hyperpolarizing factors

Autor: Batenburg, Wendy W, Kappers, Mariette HW, Eikmann, Melissa J, Ramzan, Serge NA, de Vries, René, Danser, AH Jan
Zdroj: Journal of Hypertension; August 2009, Vol. 27 Issue: 8 p1631-1640, 10p
Abstrakt: Light-induced relaxation depends on S-nitrosothiols. S-Nitrosothiols may also serve as endothelium-derived hyperpolarizing factors, mediating the relaxant response of porcine coronary arteries (PCAs) to bradykinin. Here we compared the mechanism of light-induced and bradykinin-induced PCA relaxation.
Databáze: Supplemental Index