Enhanced postmyocardial infarction fibrosis via stimulation of the transforming growth factor-β-Smad2 signaling pathway role of transient receptor potential vanilloid type 1 channels

Autor: Huang, Wei, Rubinstein, Jack, Prieto, Alejandro R, Wang, Donna H
Zdroj: Journal of Hypertension; February 2010, Vol. 28 Issue: 2 p367-376, 10p
Abstrakt: To test the hypothesis that the transient receptor potential vanilloid type 1 (TRPV1) channels modulate postmyocardial infarction (MI) fibrosis and matrix formation via the transforming growth factor-β-Smad signaling pathway to conserve cardiac function and geometrical regeneration.
Databáze: Supplemental Index