Enhanced postmyocardial infarction fibrosis via stimulation of the transforming growth factor-β-Smad2 signaling pathway role of transient receptor potential vanilloid type 1 channels
Autor: | Huang, Wei, Rubinstein, Jack, Prieto, Alejandro R, Wang, Donna H |
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Zdroj: | Journal of Hypertension; February 2010, Vol. 28 Issue: 2 p367-376, 10p |
Abstrakt: | To test the hypothesis that the transient receptor potential vanilloid type 1 (TRPV1) channels modulate postmyocardial infarction (MI) fibrosis and matrix formation via the transforming growth factor-β-Smad signaling pathway to conserve cardiac function and geometrical regeneration. |
Databáze: | Supplemental Index |
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