Effect of time and exercise on the clearance rate of 201Tl in normal and ischemic myocardium

Autor: Backus, Barbra E., Hezemans, Rachel E.L., Verburg, Frederik A., Keijsers, Ruth G.M., Konijnenberg, Mark W., Verzijlbergen, J. Fred
Zdroj: Nuclear Medicine Communications; June 2010, Vol. 31 Issue: 6 p539-546, 8p
Abstrakt: Simultaneous dual isotope (SDI) acquisition of 201Tl rest99mTc-sestamibi stress-myocardial perfusion single photon emission computed tomography is a desirable new procedure in nuclear cardiology. In this protocol 201Tl is injected at rest but imaging is performed not earlier than after exercise. Therefore, one must be convinced that throughout exercise 201Tl remains distributed in an identical pattern as at rest. Before SDI can be applied clinically, 201Tl rest MPS before and after exercise test needs to be compared for equality. The aim of this study was to assess the effect of time and exercise on the clearance of preinjected 201Tl in normal and ischemic myocardium.
Databáze: Supplemental Index