Radiosynthesis of 18F-(R8,15,21, L17)-vasoactive intestinal peptide and preliminary evaluation in mice bearing C26 colorectal tumours

Autor: Cheng, Dengfeng, Yin, Duanzhi, Zhang, Lan, Wang, Mingwei, Li, Gucai, Wang, Yongxian
Zdroj: Nuclear Medicine Communications; June 2007, Vol. 28 Issue: 6 p501-506, 6p
Abstrakt: Radiolabelled vasoactive intestinal peptide (VIP) and its analogues have shown their potential as imaging agents for diagnosing tumours expressing VIP receptor. However, the fast proteolytic degradation in vivohas limited their clinical use.
Databáze: Supplemental Index