| Autor: |
Jessup, Jewell A., Zhang, Lili, Chen, Alex F., Presley, Tennille D., Kim-Shapiro, Daniel B., Chappell, Mark C., Wang, Hao, Groban, Leanne |
| Zdroj: |
Menopause; June 2011, Vol. 18 Issue: 6 p698-708, 11p |
| Abstrakt: |
The loss of estrogen in mRen2.Lewis rats leads to an exacerbation of diastolic dysfunction. Because specific neuronal nitric oxide synthase (nNOS) inhibition reverses renal damage in the same model, we assessed the effects of inhibiting neuronal nitric oxide on diastolic function, left ventricular remodeling, and the components of the cardiac nitric oxide system in ovariectomized (OVX) and sham-operated mRen2.Lewis rats treated with N5-(1-imino-3-butenyl)-L-ornithine (L-VNIO; 0.5 mg/kg per day for 28 d) or vehicle (saline). |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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