| Autor: |
Wanrooy, Marjolijn J. P. van, Santoe, Riaaz N., Elst, Kim C. M. van der, Wilmer, Carli M., van Hateren, Kai, Wessels, A. Mireille A., Greijdanus, Ben, Alffenaar, Jan-Willem C., Uges, Donald R. A. |
| Zdroj: |
Therapeutic Drug Monitoring; December 2013, Vol. 35 Issue: 6 p778-784, 7p |
| Abstrakt: |
Echinocandins are a valuable addition for the treatment of invasive fungal infections, as they are efficacious, demonstrate low toxicity, and have limited drug–drug interactions. In specific clinical situations when altered pharmacokinetics can be expected or dosing guidelines are conflicting, it may be useful to measure concentrations. For this purpose, a liquid chromatography tandem mass-spectrometric method to measure anidulafungin and caspofungin in ethylenediaminetetraacetic acid plasma was developed. |
| Databáze: |
Supplemental Index |
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