Common Genetic Variation in the 3′-BCL11BGene Desert Is Associated With Carotid-Femoral Pulse Wave Velocity and Excess Cardiovascular Disease Risk

Autor: Mitchell, Gary F., Verwoert, Germaine C., Tarasov, Kirill V., Isaacs, Aaron, Smith, Albert V., Yasmin, Rietzschel, Ernst R., Tanaka, Toshiko, Liu, Yongmei, Parsa, Afshin, Najjar, Samer S., O'Shaughnessy, Kevin M., Sigurdsson, Sigurdur, Buyzere, Marc L. De, Larson, Martin G., Sie, Mark P.S., Andrews, Jeanette S., Post, Wendy S., Mattace-Raso, Francesco U.S., McEniery, Carmel M., Eiriksdottir, Gudny, Segers, Patrick, Vasan, Ramachandran S., Rijn, Marie Josee E. van, Howard, Timothy D., McArdle, Patrick F., Dehghan, Abbas, Jewell, Elizabeth S., Newhouse, Stephen J., Bekaert, Sofie, Hamburg, Naomi M., Newman, Anne B., Hofman, Albert, Scuteri, Angelo, De Bacquer, Dirk, Arfan Ikram, Mohammad, Psaty, Bruce M., Fuchsberger, Christian, Olden, Matthias, Wain, Louise V., Elliott, Paul, Smith, Nicholas L., Felix, Janine F., Erdmann, Jeanette, Vita, Joseph A., Sutton-Tyrrell, Kim, Sijbrands, Eric J.G., Sanna, Serena, Launer, Lenore J., De Meyer, Tim, Johnson, Andrew D., Schut, Anna F.C., Herrington, David M., Rivadeneira, Fernando, Uda, Manuela, Wilkinson, Ian B., Aspelund, Thor, Gillebert, Thierry C., Van Bortel, Luc, Benjamin, Emelia J., Oostra, Ben A., Ding, Jingzhong, Gibson, Quince, Uitterlinden, André G., Abecasis, Gonçalo R., Cockcroft, John R., Gudnason, Vilmundur, Backer, Guy G. De, Ferrucci, Luigi, Harris, Tamara B., Shuldiner, Alan R., Duijn, Cornelia M. van, Levy, Daniel, Lakatta, Edward G., Witteman, Jacqueline C.M.
Zdroj: Circulation: Cardiovascular Genetics; February 2012, Vol. 5 Issue: 1 p81-90, 10p
Abstrakt: Carotid-femoral pulse wave velocity (CFPWV) is a heritable measure of aortic stiffness that is strongly associated with increased risk for major cardiovascular disease events.
Databáze: Supplemental Index