| Autor: |
Kwee, Sandi A., Lim, John, Coel, Marc N. |
| Zdroj: |
Clinical Nuclear Medicine; November 2017, Vol. 42 Issue: 11 p868-871, 4p |
| Abstrakt: |
Two patients with castrate-resistant prostate cancer and symptomatic skeletal metastases underwent 18F-fluorocholine PET/CT prior to treatment with 223Ra-dichloride to reveal additional active lesions in the prostate gland and lymph nodes. Subsequent scans performed at the midpoint and end of 223Ra-dichloride therapy showed resolution of this soft tissue activity alongside declining bone lesion activity. Concomitant increases in plasma interleukin 6 were detected, suggesting that immune system activation may have mediated the soft tissue response. Abscopal effects usually encountered with external beam radiotherapy may also be occurring with 223Ra-dichloride therapy. |
| Databáze: |
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| Externí odkaz: |
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