Platelet Thromboxane A2Secretion in Patients With Major Depression Responsive to Electroconvulsive Therapy

Autor: Bruce, Erica C., Guo, Ying, Lawson, Kathryn C., Manatunga, Amita K., Auyeung, S Freda, McDonald, William M., Rushing, Natasha, Brown, Angelo R., Gilles, Natalie, Emery, Milburn, Bonsall, Robert, Porquez, Jocelyn, Stowe, Zachary, Nemeroff, Charles B., Musselman, Dominique L.
Zdroj: Psychosomatic Medicine (Ovid); April 2008, Vol. 70 Issue: 3 p319-327, 9p
Abstrakt: To determine a) whether clinical response to electroconvulsive therapy (ECT) is associated with decreased platelet activation in patients with major depressive disorder (MDD) and b) if any medical/demographic characteristics predict response to ECT or changes in platelet activation. Increased platelet activation may underlie the increased risk of coronary artery disease (CAD) in patients with MDD.
Databáze: Supplemental Index