| Autor: |
Li, Francois Y.L., Lam, Karen S.L., Tse, Hung-Fat, Chen, Cheng, Wang, Yiqun, Vanhoutte, Paul M., Xu, Aimin |
| Zdroj: |
Circulation (Ovid); September 2012, Vol. 126 Issue: 10 p1267-1277, 11p |
| Abstrakt: |
Endothelial damage and dysfunction are crucial mediators that link diabetes mellitus with atherosclerotic cardiovascular disease. AMP-activated kinase (AMPK) has been implicated in regulation of both energy metabolism and vascular homeostasis. The present study investigated whether endothelium-selective activation of AMPK prevents diabetes mellitus–induced endothelial damage and vascular dysfunction by improving reendothelialization in mice. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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