| Autor: |
Reid, A. W., Anderson, B. J., Futter, M. E., Holford, N. H. G. |
| Zdroj: |
Anaesthesia and Intensive Care; October 1997, Vol. 25 Issue: 5 p525-527, 3p |
| Abstrakt: |
A nine-month infant, weighing 9.8 kg, presented with hypotonia secondary to acute hypokalaemia (1.0 mmol/l). Muscle strength improved as the serum potassium was increased. Muscle strength was assessed by the pressure generated inside a saline-filled endotracheal tube cuff during a grasp reflex. Potassium concentration and hand grip strength were related using a sigmoidal Emax model. Zero effect was assumed when the potassium concentration was zero. The Emax, EC50and Hill coefficient values were determined by non-linear regression using the MKMODEL program. Parameter estimates (SE) were EC501.79 (0.15) mmol/l, Hill coefficient 3.79 (0.92), Emax 114.4 (8.9) mmHg. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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