| Autor: |
Rocha, Andreia Maria Camargos, Rocha, Gifone Aguiar, Queiroz, Dulciene Maria de Magalhães, Ani, Agatha E, Okeke, E N, Bello, C S S, Malu, A O |
| Zdroj: |
Tropical Doctor; July 2001, Vol. 31 Issue: 3 p147-149, 3p |
| Abstrakt: |
The prevalence of antibodies to CagA protein was evaluated in 174 Helicobacter pylori-positive subjects: 110 patients submitted to upper gastrointestinal endoscopy and 64 male blood donors. The patients were from different regions of Nigeria: Jos, North, Benue, West and East and the blood donors were from Jos. Sera were assayed for anti-CagA antibodies using Helicobacter p120, CagA ELISA (Viva Diagnostika, Hürth, Germany). Anti-CagA antibodies were detected in 104 (94.5%) patients and in 61 (95.3%) blood donors (P=1.0). Patients from the Benue region presented a lower frequency of anti-CagA antibodies than patients from the other regions (P=0.0004). When the subjects were stratified by age, a significant increase in IgG concentration was observed among the men (P=0.03) but not among the women (P=0.57) or among the blood donors (P=0.83). In conclusion, similarly to Asian countries, CagA-positive H. pyloriinfection is highly frequent in Nigeria. |
| Databáze: |
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