| Autor: |
Waisbren, S. E., Zaff, J. |
| Zdroj: |
Journal of Inherited Metabolic Disease; September 1994, Vol. 17 Issue: 5 p584-592, 9p |
| Abstrakt: |
Twenty-eight young women with phenylketonuria (PKU) attending a Maternal PKU Summer Camp were interviewed and administered a personality inventory, the Minnesota Multiphasic Personality Inventory (MMPI). The 12 young women who were either late-treated (treatment initiated after 90 days) or who had terminated the diet for a period of at least 5 years (the extended exposure group) were compared to the 16 women who were early-treated and had remained continuously on diet (the continuously treated group). Although the mean blood phenylalanine and tyrosine concentrations at the camp for the two groups were comparable (973±344 and 1033±284 µmol/L for phenylalanine and 43±16 and 40±25 µmol/L for tyrosine), the women in the extended exposure group evidenced significantly greater psychopathology as measured by the MMPI and self-report; thought disorder and mood disturbances were associated with diet termination in PKU. |
| Databáze: |
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