| Autor: |
Sitprija, V., Indraprasit, S., Pochanugool, C., Benyajati, C., Piyaratn, P. |
| Zdroj: |
The Lancet; January 1967, Vol. 289 Issue: 7483 p185-188, 4p |
| Abstrakt: |
Renal failure of short duration was observed in three patients who had a heavy infestation of Plasmodium falciparum.This was associated with a low urine-sodium, a retained ability of tubular reabsorption of water, and non-remarkable urine findings. There was no evidence of dehydration or intravascular hæmolysis. Further investigations revealed a decrease in endogenous creatinine and p-aminohippurate clearances. Blood-volumes were normal. Renal biopsy showed focal vacuolisation of the proximal convoluted tubules, but no other abnormalities. The glomeruli were normal. Renal function returned to normal after treatment with intravenous and oral quinine. The renal failure may have been caused by decreased renal perfusion. This mild renal failure might easily be overlooked, but it is clinically important because excess parenteral fluids given during the period of unrecognised impairment could lead to pulmonary œdema and acute water intoxication. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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