PLATELET AGGREGATES IN PERIPHERAL AND CORONARY-SINUS BLOOD IN PATIENTS WITH SPONTANEOUS CORONARY-ARTERY SPASM

Autor: Marie Robertson, Rose, Robertson, David, Timmons, Sheila, Friesinger, GottliebC., Hawiger, Jack
Zdroj: The Lancet; October 1980, Vol. 316 Issue: 8199 p829-831, 3p
Abstrakt: Five out of twenty patients with vasotonic angina had frequent spontaneous attacks with dramatic ST-segment alterations. These attacks were consistently associated with an increase in platelet aggregates in coronary-sinus blood but not arterial blood. This increase in platelet aggregates during coronary-artery spasm suggests a potential causal role for the platelet in this subset of patients with ischæmic heart-disease. However, the increase in platelet aggregates could be secondary to reduced coronary blood-flow.
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