| Autor: |
Lawson, A.A.H., Strong, J.A., Roscoe, P., Gibson, Anna, Peattie, Patricia |
| Zdroj: |
The Lancet; August 1970, Vol. 296 Issue: 7670 p437-441, 5p |
| Abstrakt: |
A double-blind trial was undertaken to compare the efficacy of fenfluramine and metformin in promoting weight reduction in thirty-four obese women. Metformin proved to be less effective than fenfluramine and a total daily dose of 3·0 g. produced unacceptable side-effects. The effect of fenfluramine in a total daily dose of 80 mg. was still evident up to 32 weeks on a reducing regimen, and was free of serious side-effects. A further double-blind trial was conducted on eighteen of these obese women after 48 weeks of continuous dietary treatment, to study the effect of fenfluramine in a total daily dosage of 160 mg. and its suitability for long-term maintenance treatment. Fenfluramine in this dosage was found to be effective and safe. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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