BACTERIAL ANTIGENS CROSS-REACTIVE WITH THE CAPSULAR POLYSACCHARIDE OF HÆMOPHILUS INFLUENZÆ TYPE b

Autor: Bradshaw, W, Parke, J.C, Schneerson, Rachel, Robbins, JohnB
Zdroj: The Lancet; May 1971, Vol. 297 Issue: 7709 p1095-1097, 3p
Abstrakt: With the use of agar plates containing anti Hœmophilus influenzœtype b serum, a halo of precipitation was observed surrounding some bacterial colonies isolated from the pharynx and rectum of humans and rabbits. This halo of precipitation was shown to be due to polysaccharides cross-reactive with the type-b polysaccharide of H. influenzœ. The demonstration of several different species of bacteria in normal individuals possessing cross-reacting antigens may provide an explanation for the development of the "natural" immunity to H. influenzœtype b observed in most adults. This technique of using antiserum agar may permit the demonstration of cross-reacting antigens to other pathogenic bacteria in mixed bacterial cultures.
Databáze: Supplemental Index