| Autor: |
Sagar, S., Thomas, D.P., Stamatakis, J.D., Kakkar, V.V. |
| Zdroj: |
The Lancet; March 1976, Vol. 307 Issue: 7958 p509-511, 3p |
| Abstrakt: |
Deep-vein thrombosis (D.V.T.) was detected by the fibrinogen-uptake test in six out of a total of thirty-one young women undergoing emergency abdominal surgery who gave a history of recent oral contraceptive intake. In contrast, no D.V.T. developed in nineteen similar patients who were not on oral contraceptives (P< 0·01). Plasma-antithrombin-III activity was significantly lower preoperatively in patients taking oral contraceptives, postoperative D.V.T. subsequently developed in three out of five patients with preoperative antithrombin-III activity below 50%. In seventy-eight dental patients undergoing molar extraction, antithrombin-III activity was measured before, during, and after operation. Activity fell in all patients during operation, but the fall was significantly greater in women taking oral contraceptives (P < 0·01). The intra-operative fall in antithrombin-III activity was prevented by a small preoperative dose of subcutaneous heparin. |
| Databáze: |
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| Externí odkaz: |
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