TERMINAL TRANSFERASE IN HUMAN BONE-MARROW LYMPHOCYTES

Autor: Barr, RonaldD., Sarin, PremS., Perry, SeymourM.
Zdroj: The Lancet; March 1976, Vol. 307 Issue: 7958 p508-509, 2p
Abstrakt: Activity of the enzyme terminal transferase (TdT) has been localised in normal human bone-marrow lymphocytes. These cells may represent a prothymocyte population, which, on malignant transformation, may give rise to acute lymphoblastic leukæmia, and to some cases of chronic granulocytic leukæmia in the blastic phase.
Databáze: Supplemental Index