PLASMA-PROLACTIN IN HUMAN BREAST CANCER

Autor: Kwa, H.G., Engelsman, E., de Jong-Bakker, M., Cleton, F.J.
Zdroj: The Lancet; March 1974, Vol. 303 Issue: 7855 p433-435, 3p
Abstrakt: Plasma-prolactin was assayed in 115 patients with breast cancer and 115 matched controls. Mean plasma-prolactin levels were 6.0 ± 3.7 ng. per ml. and 5.9 ± 2.9 ng. per ml., respectively. Plasma-prolactin levels were normally distributed in both groups. Plasma levels in 64 members of nine families with a high frequency of breast cancer were irregularly distributed, with a mean prolactin level of 10.4 ± 8.1 ng. per ml. Statistical evaluation demonstrated that breast-cancer patients and controls may be regarded as one population but that the prolactin levels in the high-risk group represent a different population (P < 0.0004).
Databáze: Supplemental Index