Autor: |
Kumar, Ashish, Jad, Yahya E., El-Faham, Ayman, Torre, Beatriz G. de la, Albericio, Fernando |
Zdroj: |
Letters in Organic Chemistry; January 2019, Vol. 16 Issue: 1 p30-33, 4p |
Abstrakt: |
A new phosphonium based coupling reagent DEPO-B has been synthesized from 5- (hydroxyimino)-1,3-dimethylpyrimidine-2,4,6 (1H,3H,5H)-trione (Oxyma B) and diethyl chlorophosphate in presence of base. It is a solid material and the hydrolytic stability and solubility was evaluated for confirming its capability for usage in automated peptide synthesizer. |
Databáze: |
Supplemental Index |
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